MedPath

IS-10506

Generic Name
IS-10506

Probiotics Show Promise in Mitigating Toxic Effects of Fire Retardant Chemicals

• A new study shows that the probiotic _Limosilactobacillus reuteri_ (LR) can reduce the negative impacts of polybrominated diphenyl ethers (PBDEs) on neurodevelopment, behavior, and metabolism in mice. • Maternal supplementation with LR corrected most of the behavioral and metabolic abnormalities caused by PBDE exposure in offspring, suggesting a protective effect against toxic exposures. • The research highlights the potential of gut microbiota-focused therapies, administered through the mother, to protect against developmental and adult diseases linked to environmental toxins. • The study found that LR supplementation promoted gut bacteria diversity in female pups and prevented changes in gut bacteria in male pups exposed to PBDEs.
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