MedPath

Malathion

Generic Name
Malathion
Brand Names
Ovide
Drug Type
Small Molecule
Chemical Formula
C10H19O6PS2
CAS Number
121-75-5
Unique Ingredient Identifier
U5N7SU872W
Background

Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.

Indication

For patients infected with Pediculus humanus capitis (head lice and their ova) of the scalp hair.

Associated Conditions
Head Lice Infestation

Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands

Phase 3
Completed
Conditions
Scabies
Head Lice
Interventions
First Posted Date
2017-08-01
Last Posted Date
2019-06-14
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
118
Registration Number
NCT03236168
Locations
🇸🇧

Atoifi Adventist Hospital, Atoifi, Malaita, Solomon Islands

Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice

Phase 3
Completed
Conditions
Pediculosis
Interventions
First Posted Date
2009-08-21
Last Posted Date
2014-06-13
Lead Sponsor
Taro Pharmaceuticals USA
Target Recruit Count
403
Registration Number
NCT00963508
Locations
🇺🇸

Investigator Site, San Antonio, Texas, United States

Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice

Phase 3
Completed
Conditions
Pediculosis
Interventions
First Posted Date
2009-06-25
Last Posted Date
2014-08-04
Lead Sponsor
Taro Pharmaceuticals USA
Target Recruit Count
254
Registration Number
NCT00927472
Locations
🇺🇸

Investigator Site, Jonesboro, Arkansas, United States

Pharmacokinetics of Malathion Gel 0.5% and Malathion 0.5% Lotion (Ovide) in Patients With Head Lice

Phase 1
Completed
Conditions
Pediculosis
Interventions
First Posted Date
2009-06-25
Last Posted Date
2013-12-24
Lead Sponsor
Taro Pharmaceuticals USA
Target Recruit Count
24
Registration Number
NCT00927407
Locations
🇮🇳

Investigator Site, Rabale, Navi Mumbai, India

Ivermectin in the Treatment of Head Lice

Phase 3
Completed
Conditions
Lice Infestations
Interventions
First Posted Date
2009-01-09
Last Posted Date
2011-08-22
Lead Sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Target Recruit Count
812
Registration Number
NCT00819520
Locations
🇮🇱

Chaim Sheba Medical Centre, Tel Hashomer, Israel

🇬🇧

Synexus Clinical Research Centre, Reading, Berks, United Kingdom

🇫🇷

Hopital Avicenne, Bobigny, Paris, France

and more 1 locations

Safety and Efficacy of a Novel Malathion Formulation in the Treatment of Head Lice

Phase 3
Completed
Conditions
Lice Infestations
Interventions
First Posted Date
2005-10-26
Last Posted Date
2013-12-23
Lead Sponsor
Taro Pharmaceuticals USA
Target Recruit Count
360
Registration Number
NCT00244439
Locations
🇺🇸

Investigator Site, Miamiville, Ohio, United States

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