Isosorbide mononitrate

Generic Name
Isosorbide mononitrate
Brand Names
Imdur, Ismo, Monoket
Drug Type
Small Molecule
Chemical Formula
C6H9NO6
CAS Number
16051-77-7
Unique Ingredient Identifier
LX1OH63030
Background

Isosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload. Isosorbide mononitrate is an active metabolite of isosorbide dinitrate. Like other organic nitrates, isosorbide mononitrate acts as ...

Indication

Isosorbide mononitrate is indicated for the prevention and management of angina pectoris due to coronary artery disease. The onset of action of oral isosorbide mononitrate is not sufficiently rapid to be useful in aborting an acute anginal episode.

Associated Conditions
Angina Pectoris
Associated Therapies
-
Clinical Trials
Related News

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First Posted Date
2022-04-22
Last Posted Date
2022-04-22
Lead Sponsor
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Target Recruit Count
60
Registration Number
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Pharmacokinetics Trial of Isosorbide Mononitrate 0.5% Gel for Intra Anal Application in Healthy Subjects

First Posted Date
2021-01-28
Last Posted Date
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Registration Number
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the Effect of Isosorbide Mononitrate in Reducing Pain During Cooper Intrauterine Device Insertion

First Posted Date
2020-03-18
Last Posted Date
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Registration Number
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Locations
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Isosorbide Mononitrate For Anti-Vascular Endothelial Growth Factor (VEGF) Induced Kidney Injury

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Registration Number
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Locations
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Using Isosorbide Mononitrate in Reducing Time in Induction of Labor in Post Date Women

First Posted Date
2019-02-26
Last Posted Date
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Registration Number
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Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes

First Posted Date
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Registration Number
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Locations
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Pain Relief During IUD Insertion in Women Delivered Only by Elective Cesarean Section

First Posted Date
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Last Posted Date
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Registration Number
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Nitric Oxide Donor Isosorbide Mono Nitrate for Cervical Ripening in Induction of Labor

First Posted Date
2018-06-04
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Misoprosotol and Isosorbide Mononitrate for Induction of Second Trimester Abortion

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Targeting Central Pulsatile Hemodynamics in Chronic Kidney Disease

First Posted Date
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Last Posted Date
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Registration Number
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