Moxifloxacin

Generic Name
Moxifloxacin
Brand Names
Avelox, Moxeza, Vigamox
Drug Type
Small Molecule
Chemical Formula
C21H24FN3O4
CAS Number
151096-09-2
Unique Ingredient Identifier
U188XYD42P
Background

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

Indication

For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).

Associated Conditions
Acute Exacerbation of Chronic Bronchitis (AECB), Bacterial Conjunctivitis, Community Acquired Pneumonia (CAP), Plague, Postoperative Infections, Postoperative Inflammatory Response, Sinusitis, Skin Infections, Ocular bacterial infections
Associated Therapies
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A Study to Investigate the Effects of Zelicapavir (EDP-938) on QTc Interval in Healthy Adults

First Posted Date
2024-09-19
Last Posted Date
2024-10-24
Lead Sponsor
Enanta Pharmaceuticals, Inc
Target Recruit Count
72
Registration Number
NCT06601192
Locations
🇺🇸

ICON Early Phase, LLC, San Antonio, Texas, United States

🇺🇸

ICON, Lenexa, Kansas, United States

A TQT Study to Investigate the Effect of Enpatoran on Cardiac Repolarization in Healthy Participants

First Posted Date
2024-09-19
Last Posted Date
2024-12-19
Lead Sponsor
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Target Recruit Count
40
Registration Number
NCT06589726
Locations
🇩🇪

Nuvisan GmbH, Neu-Ulm, Germany

A Study to Find Out How Multiple Doses of BIIB091 Affect the Electrical Activity of the Heart in Healthy Participants

First Posted Date
2024-08-28
Last Posted Date
2024-11-01
Lead Sponsor
Biogen
Target Recruit Count
64
Registration Number
NCT06574828
Locations
🇺🇸

Austin Clinic PPD, Austin, Texas, United States

Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis

First Posted Date
2024-06-04
Last Posted Date
2024-12-05
Lead Sponsor
University of California, San Francisco
Target Recruit Count
690
Registration Number
NCT06441006
Locations
🇲🇩

Institute of Phthisiopneumology Chiril Dragniuc, Chisinau, Moldova, Republic of

🇲🇳

National Center for Communicable Diseases, Ulaanbaatar, Mongolia

🇵🇪

Hospital Nacional Hipólito Unanue, Lima, Peru

and more 7 locations

A Study to Evaluate the Effect of Povorcitinib on the QT/QTc Interval in Healthy Participants

First Posted Date
2024-06-04
Last Posted Date
2024-07-25
Lead Sponsor
Incyte Corporation
Target Recruit Count
128
Registration Number
NCT06441318
Locations
🇺🇸

Celerion Clinical Research Unit, Tempe, Arizona, United States

A Study to Assess the Effect of Olpasiran on QT/QTc Intervals in Healthy Participants

First Posted Date
2024-05-13
Last Posted Date
2024-12-20
Lead Sponsor
Amgen
Target Recruit Count
32
Registration Number
NCT06411860
Locations
🇬🇧

Fortrea Clinical Research Unit Limited - Leeds, Leeds, United Kingdom

A Study to Evaluate the Effects of HSK3486 Administration on Cardiac Repolarization in Healthy Subjects

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2024-04-23
Last Posted Date
2024-04-26
Lead Sponsor
Haisco Pharmaceutical Group Co., Ltd.
Target Recruit Count
48
Registration Number
NCT06379867
Locations
🇨🇳

Beijing GoBroad Boren Hospital, Beijing, China

A Study of TAK-279 in Healthy Adults on the Effect on ECG Measurements

First Posted Date
2024-02-14
Last Posted Date
2024-07-11
Lead Sponsor
Takeda
Target Recruit Count
120
Registration Number
NCT06258265
Locations
🇺🇸

Celerion, Tempe, Arizona, United States

Shortened Regimen for Drug-susceptible TB in Children

First Posted Date
2024-02-12
Last Posted Date
2024-12-05
Lead Sponsor
Johns Hopkins University
Target Recruit Count
860
Registration Number
NCT06253715
Locations
🇮🇳

Indian Council of Medical Research - National Institute for Research in Tuberculosis, Chennai, India

🇮🇳

Dr. D.Y. Patil Medical College, Hospital and Research Center, Pimpri, Pune, India

🇮🇩

Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia

and more 4 locations

A Study to Evaluate the Effect of Pirtobrutinib (LOXO-305) on QTc Interval in Healthy Participants

Phase 1
Completed
Conditions
Interventions
First Posted Date
2024-01-22
Last Posted Date
2024-01-22
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
31
Registration Number
NCT06215521
Locations
🇺🇸

Covance Clinical Research Unit 1341 Mockingbird Lane, Dallas, Texas, United States

🇺🇸

Covance Clinical Research Unit 3402 Kinsman Blvd, Madison, Wisconsin, United States

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