莫西沙星 (Avelox, Moxeza, Vigamox)

概览

Moxifloxacin is a fluoroquinolone antibiotic used to treat various bacterial infections.

作用机制

The bactericidal action of moxifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division.

适应症

For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).

• Acute Exacerbation of Chronic Bronchitis (AECB)
• Bacterial Conjunctivitis
• Community Acquired Pneumonia (CAP)
• Plague
• Postoperative Infections
• Postoperative Inflammatory Response
• Sinusitis
• Skin Infections
• Ocular bacterial infections