Meclofenamic acid

Generic Name: Meclofenamic acid

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: C_₁₄H_₁₁Cl_₂NO_₂

CAS Number: 644-62-2

Unique Ingredient Identifier: 48I5LU4ZWD

Background: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.

Indication: For the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.

Associated Conditions: Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Fever, Hypermenorrhea, Juvenile Idiopathic Arthritis (JIA), Mild pain, Osteoarthritis (OA), Primary Dysmenorrhoea, Rheumatoid Arthritis, Acute Subacromial bursitis, Moderate Pain, Supraspinatus tendinitis

Associated Therapies: -

Clinical Trials

Probenecid: Package Insert / Prescribing Information

Probenecid is a uricosuric agent used to treat hyperuricemia in gout and as an adjuvant to penicillin therapy to elevate plasma levels. It inhibits urate reabsorption, increasing uric acid excretion. Contraindicated in children under 2, those with hypersensitivity, blood dyscrasias, or uric acid kidney stones. Warnings include exacerbation of gout, increased methotrexate toxicity, and contraindication with salicylates. Precautions involve monitoring for renal impairment and drug interactions. Adverse reactions include CNS, metabolic, gastrointestinal, genitourinary, hypersensitivity, hematologic, and integumentary effects. Dosage varies for gout and penicillin therapy, with specific recommendations for adults and children.

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.