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Cangrelor

Generic Name
Cangrelor
Brand Names
Kengreal, Kengrexal
Drug Type
Small Molecule
Chemical Formula
C17H25Cl2F3N5O12P3S2
CAS Number
163706-06-7
Unique Ingredient Identifier
6AQ1Y404U7

Overview

Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset and offset of action. Cangrelor was approved by the FDA in June 2015 for intravenous application.

Background

Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset and offset of action. Cangrelor was approved by the FDA in June 2015 for intravenous application.

Indication

For use as an adjunct to percutaneous coronary intervention (PCI) for reducing the risk of periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST) in patients in who have not been treated with a P2Y12 platelet inhibitor and are not being given a glycoprotein IIb/IIIa inhibitor.

Associated Conditions

  • Coronary Revascularization
  • Peri-procedural Myocardial Infarction
  • Thrombosis (Stent Thrombosis)

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

No Singapore products found for this drug

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