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Cetylpyridinium chloride

Generic Name
Cetylpyridinium chloride
Brand Names
Cepacol Antibacterial Mouthwash, Crest Mouthwash, Orajel Bleeding Gum Rinse, Orasep Reformulated Dec 2013
Drug Type
Small Molecule
Chemical Formula
C21H38N
CAS Number
7773-52-6
Unique Ingredient Identifier
CUB7JI0JV3

Overview

Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.

Background

Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.

Indication

Typically employed as the cetylpyridinium chloride salt, this compound is commonly used as an active ingredient in various over-the-counter mouthwashes, toothpastes, lozenges, and mouth sprays where it is generally indicated for antiseptic actions, gingivitis and plaque prevention, as well as action or prevention against some other oropharyngeal bacterial infections .

Associated Conditions

  • Gingivitis
  • Oral Pain
  • Pain, Orofacial
  • Sore Throat
  • Stomatitis
  • Teething pain
  • Throat irritation
  • Dry cough
  • Gum pain
  • Oral discomfort and pain
  • Oral infections
  • Pain in throat
  • Throat infections
  • Throat inflammation

FDA Approved Products

Mint Alcohol Free
Manufacturer:WinCo Foods LLC
Route:ORAL
Strength:0.7 mg in 1 mL
Approved: 2025/05/22
NDC:67091-462

Singapore Approved Products

Difflam™ Anti-inflammatory Lozenge (with antibacterial) (Eucalyptus and Menthol)
Manufacturer:Unique Pharmaceuticals Laboratories
Form:LOZENGE
Strength:1.33mg
Online:Yes
Approved: 2009/01/22
Approval:SIN13591P

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