Brinzolamide

Generic Name
Brinzolamide
Brand Names
Azarga, Azopt, Simbrinza
Drug Type
Small Molecule
Chemical Formula
C12H21N3O5S3
CAS Number
138890-62-7
Unique Ingredient Identifier
9451Z89515
Background

Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase II (CA-II) inhibitor indicated to reduce ocular pressure in patients with ocular hypertension or open-angle glaucoma. Although the exact pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and abnormalities. The resu...

Indication

Brinzolamide, either as a standalone agent or in combination with brimonidine, is approved by the FDA for the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Brinzolamide is also approved in Europe to be used in combination with timolol to treat the same conditions.

Associated Conditions
Increased Intra Ocular Pressure (IOP)
Associated Therapies
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