Creatine

Generic Name: Creatine

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: C_₄H_₉N_₃O_₂

CAS Number: 57-00-1

Unique Ingredient Identifier: MU72812GK0

Background: An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.

Indication: For nutritional supplementation, also for treating dietary shortage or imbalance.

Associated Conditions: -

Associated Therapies: -

Clinical Trials

Effects of Creatine Supplementation on Muscle Mass and Function Among Older Women Subjected to Resistance Training

Phase 3

Completed

Conditions: Muscle Weakness

Interventions: Other: Resistance exercise training
Drug: Creatine

First Posted Date: 2014-07-14

Last Posted Date: 2015-10-30

Lead Sponsor: University of Chile

Target Recruit Count: 50

Registration Number: NCT02188849

Locations: 🇨🇱
INTA University of Chile, Santiago, Metropolitan, Chile

Creatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive Disorder

Phase 4

Completed

Conditions: Major Depressive Disorder

Interventions: Drug: Creatine
Drug: Placebo

First Posted Date: 2014-05-09

Last Posted Date: 2024-07-03

Lead Sponsor: Perry Renshaw

Target Recruit Count: 71

Registration Number: NCT02134808

Locations: 🇺🇸
University of Utah School of Medicine, Salt Lake City, Utah, United States

A Clinical Study to Investigate the Effects of Creatine Supplementation on Muscle Energetics and Cognitive Function in Young Healthy Male Athletes and an Ageing Population

Phase 1

Completed

Conditions: Nutritional Status

Interventions: Drug: Placebo
Drug: Creatine

First Posted Date: 2014-02-10

Last Posted Date: 2018-03-23

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 30

Registration Number: NCT02058654

Locations: 🇬🇧
GSK Investigational Site, London, United Kingdom

Safety and Efficacy Study of Creatine and Tamoxifen in Volunteers With Amyotrophic Lateral Sclerosis (ALS)

Phase 2

Completed

Conditions: Amyotrophic Lateral Sclerosis

Interventions: Drug: creatine
Drug: tamoxifen

First Posted Date: 2010-12-09

Last Posted Date: 2014-12-04

Lead Sponsor: Nazem Atassi

Target Recruit Count: 60

Registration Number: NCT01257581

Locations: 🇺🇸
SUNY Upstate Medical University, Syracuse, New York, United States
🇺🇸
Pennsylvania State University, Hershey Medical Center, Hershey, Pennsylvania, United States
🇺🇸
University of Massachusetts Medical Center, Worcester, Massachusetts, United States

and more 6 locations

Creatine Augmentation in Veterans With SSRI-Resistant Major Depression

Phase 4

Withdrawn

Conditions: Major Depressive Disorder

Interventions: Drug: Creatine

First Posted Date: 2010-08-05

Last Posted Date: 2016-08-15

Lead Sponsor: University of Utah

Registration Number: NCT01175616

NET-PD LS-1 Creatine in Parkinson's Disease

Phase 3

Terminated

Conditions: Parkinson's Disease

Interventions: Other: placebo
Drug: creatine

First Posted Date: 2007-03-21

Last Posted Date: 2015-04-02

Lead Sponsor: University of Rochester

Target Recruit Count: 1741

Registration Number: NCT00449865

Locations: 🇺🇸
Northshore-LIJ Health System, The Feinstein Institute FPR Medical Research, 350 Community Drive Room,, Manhasset, New York, United States
🇺🇸
Indiana University School Of Medicine, Outpatient Clinical Research Facility, 535 Barnhill Drive Room #150, Indianapolis, Indiana, United States
🇺🇸
Brigham & Women's Hospital, Neurology Department ASB2, 75 Francis Street, Boston, Massachusetts, United States

and more 47 locations

Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis

Phase 2

Completed

Conditions: Amyotrophic Lateral Sclerosis

Interventions: Drug: Creatine
Drug: Celecoxib
Drug: Minocycline

First Posted Date: 2006-07-24

Last Posted Date: 2011-02-01

Lead Sponsor: Columbia University

Target Recruit Count: 86

Registration Number: NCT00355576

Locations: 🇺🇸
UT Southwestern Medical Center, Dallas, Texas, United States
🇺🇸
UMDNJ, New Brunswick, New Jersey, United States
🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

and more 16 locations

Dietary Supplements for the Treatment of Angelman Syndrome

Not Applicable

Completed

Conditions: Angelman Syndrome
Nervous System Diseases

Interventions: Drug: Betaine
Drug: Creatine
Drug: Metafolin
Drug: Vitamin B12

First Posted Date: 2006-07-06

Last Posted Date: 2012-09-24

Lead Sponsor: University of California, San Diego

Target Recruit Count: 90

Registration Number: NCT00348933

Locations: 🇺🇸
Baylor College of Medicine, Houston, Texas, United States
🇺🇸
Rady Children's Hospital San Diego, San Diego, California, United States
🇺🇸
Children's Hospital Boston, Boston, Massachusetts, United States

and more 1 locations

Creatine Treatment in Psychiatric Disorders

Phase 3

Completed

Conditions: Schizophrenia

First Posted Date: 2005-09-01

Last Posted Date: 2009-07-29

Lead Sponsor: Beersheva Mental Health Center

Target Recruit Count: 12

Registration Number: NCT00140192

Locations: 🇮🇱
Beersheva Mental Health Center, Beersheva, Israel

National Institute of Neurological Disorders and Stroke (NINDS) Parkinson's Disease Neuroprotection Trial

Phase 2

Completed

Conditions: Parkinson's Disease

First Posted Date: 2003-06-25

Last Posted Date: 2016-01-20

Lead Sponsor: University of Rochester

Target Recruit Count: 195

Registration Number: NCT00063193

Locations: 🇺🇸
University of Rochester Medical Center, Rochester, New York, United States

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2024. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy