MedPath

REC-994

Generic Name
REC-994
Brand Names
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Drug Type
Small Molecule
Chemical Formula
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CAS Number
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Unique Ingredient Identifier
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Background

REC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous malformation (CCM).

Associated Conditions
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Associated Therapies
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etfdailynews.com
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Recursion Pharmaceuticals (NASDAQ:RXRX) Shares Down 0.1% – Here’s What Happened

Recursion Pharmaceuticals shares slightly dropped to $6.76, with a 74% increase in trading volume. Analysts set a $11.00 target price, maintaining a 'Hold' consensus. The company reported a miss in quarterly earnings but a significant revenue increase. Insiders sold shares, while institutional investors increased stakes. Recursion focuses on drug discovery through technology integration.
etfdailynews.com
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Recursion Pharmaceuticals (NASDAQ:RXRX) Stock Price Down 4.6% – Here’s What Happened

Recursion Pharmaceuticals' stock fell 4.6% to $7.31, with trading volume down 12%. Analysts have mixed ratings, with an average 'Hold' and a $9.25 target. The company reported a ($0.34) EPS miss but a 147.6% revenue increase. Insiders sold shares, and institutional investors adjusted holdings, owning 89.06% of the stock.
aol.com
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1 Artificial Intelligence (AI) Stock That Could Soar in 2025

Recursion Pharmaceuticals, an AI-focused biotech, could see significant progress in 2025, potentially boosting its stock. The company uses AI to accelerate drug discovery and development, with collaborations including Nvidia. Recent clinical trial results are encouraging, but the stock remains risky. Investors should consider the potential upside and volatility.
insidermonkey.com
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Why Recursion Pharmaceuticals (RXRX) Is the Worst ARK Stock to Buy According to Short Sellers

Cathie Wood's ARK Invest focuses on disruptive innovation, with holdings fluctuating from $16.8B in Q3 2020 to $13B in Q3 2023. Despite some losses, Wood's strategy includes diversification and a belief in mean reversion. Recursion Pharmaceuticals, with a 22.53% short interest, is highlighted among ARK's worst stocks, despite its innovative drug trials and partnerships.
genengnews.com
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Trans-Atlantic Triumph: AI Drug Pioneers Recursion, Exscientia Combine

Recursion and Exscientia complete AI-based drug development merger, creating a trans-Atlantic powerhouse with over 30 clinical and preclinical programs. The combined company, headquartered in Salt Lake City, focuses on oncology and rare diseases, with REC-617 (CDK7 inhibitor) and REC-994 (CCM treatment) as key candidates. The merger aims to generate $100 million in annual savings through operational synergies, including job cuts, and expects to receive over $20 billion in additional milestone payments from partnerships with Roche, Sanofi, Bayer, and others.
nz.finance.yahoo.com
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Recursion and Exscientia Combine to Advance the Industrialization of Drug Discovery

Recursion Pharmaceuticals completed its business combination with Exscientia, creating a leading AI-enabled drug discovery platform. The combined entity boasts over 10 clinical/preclinical programs, 10 advanced discovery programs, and 10+ partnered programs, aiming to reduce drug discovery time and cost. Updates on pipeline progress and partnerships were shared, with key data expected in 2024-2026.
pymnts.com
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The Week in AI: 'Safe' Superintelligence and Human Authentication

OpenAI co-founder Ilya Sutskever's new venture, Safe Superintelligence (SSI), secures $1 billion for 'safe' superintelligence. AI-driven drug discovery faces challenges in clinical trials, while tech giants race to perfect multilingual chatbots. Researchers unveil 'personhood credentials' to distinguish humans from AI online.
pymnts.com
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AI Drug Discovery Trial Reveals Promise and Challenges of Using the Tech

AI's potential in drug discovery is highlighted by Recursion Pharmaceuticals' Phase 2 SYCAMORE trial for REC-994, targeting cerebral cavernous malformation, which met safety endpoints but showed mixed efficacy. Despite AI's ability to analyze vast datasets, challenges include data scarcity for rare conditions and predicting drug efficacy accurately. Experts suggest developing more complex AI models and combining AI with traditional techniques to advance drug discovery.
statnews.com
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Recursion presents mixed data on lead AI-derived drug candidate for potentially fatal brain condition

Recursion Pharmaceuticals announced successful results for its lead drug candidate REC-994, showing it safe and tolerable for cerebral cavernous malformation patients in a Phase 2 study, though likely not satisfying investors closely watching the AI drug developer.
investing.com
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Recursion announces positive phase 2 trial results for CCM drug

Recursion announced Phase 2 SYCAMORE trial results for REC-994, a CCM treatment, showing safety and promising MRI-based efficacy at the highest dose. The study, involving 62 participants, met primary safety endpoints but lacked significant patient-reported improvements. Recursion plans further FDA discussions and data publication. CCM affects 360,000 in the US and EU5, with Recursion leveraging its Recursion OS for drug development.
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