Aztreonam
- Generic Name
- Aztreonam
- Brand Names
- Azactam, Cayston
- Drug Type
- Small Molecule
- Chemical Formula
- C13H17N5O8S2
- CAS Number
- 78110-38-0
- Unique Ingredient Identifier
- G2B4VE5GH8
- Background
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
- Indication
For the treatment of the following infections caused by susceptible gram-negative microorganisms: urinary tract infections, lower respiratory tract infections, septicemia, skin and skin-structure infections, intra-abdominal infections, and gynecologic infections.
- Associated Conditions
- Bone and Joint Infections, Cystic Fibrosis (CF), Febrile Neutropenia, Gynecological Infection, Intraabdominal Infections, Lower Respiratory Tract Infection (LRTI), Osteomyelitis, Septic Arthritis, Septicemia, Skin Infections, Urinary Tract Infection, Uncomplicated Gonorrhea
- Associated Therapies
- -
Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections
Phase 3
Completed
- Conditions
- Complicated Skin and Soft Tissue Infection
- Interventions
- First Posted Date
- 2011-12-26
- Last Posted Date
- 2017-09-06
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 802
- Registration Number
- NCT01499277
- Locations
- 🇺🇦
Research Site, Odesa, Ukraine
Efficacy and Safety of Ceftaroline Versus Linezolid in Subjects With Complicated Skin and Skin Structure Infections
Phase 2
Completed
- Conditions
- Bacterial Infection
- Interventions
- First Posted Date
- 2008-03-11
- Last Posted Date
- 2017-03-14
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 150
- Registration Number
- NCT00633152
- Locations
- 🇺🇸
Investigational Site, Toledo, Ohio, United States
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