Diethylstilbestrol
- Generic Name
- Diethylstilbestrol
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C18H20O2
- CAS Number
- 56-53-1
- Unique Ingredient Identifier
- 731DCA35BT
- Background
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)
The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.
- Indication
Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
- Associated Conditions
- -
- Associated Therapies
- -
Dexamethasone, Aspirin, and Diethylstilbestrol in Treating Patients With Locally Advanced or Metastatic Prostate Cancer
- Conditions
- Prostate Cancer
- First Posted Date
- 2006-04-21
- Last Posted Date
- 2013-06-26
- Lead Sponsor
- St. Bartholomew's Hospital
- Target Recruit Count
- 260
- Registration Number
- NCT00316927
- Locations
- 🇬🇧
Kent and Canterbury Hospital, Canterbury, England, United Kingdom
🇬🇧Chelsea Westminster Hospital, London, England, United Kingdom
🇬🇧Milton Keynes General Hospital, Milton Keynes, England, United Kingdom
Drug Development Updates
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