Paliperidone

Generic Name
Paliperidone
Brand Names
Invega, Invega Hafyera, Xeplion, Niapelf, Byannli (previously Paliperidone Janssen-Cilag International), Trevicta (previously Paliperidone Janssen), ERZOFRI
Drug Type
Small Molecule
Chemical Formula
C23H27FN4O3
CAS Number
144598-75-4
Unique Ingredient Identifier
838F01T721
Background

Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism. Paliperido...

Indication

As an oral extended-release tablet and a once-monthly extended-release suspension for intramuscular injection, paliperidone is indicated for the treatment of adults and adolescents with schizophrenia and in the treatment of schizoaffective disorder in combination with antidepressants or mood stabilizers. Paliperidone is also available in both an every-three-...

Associated Conditions
Schizoaffective Disorders, Schizophrenia
Associated Therapies
-
Clinical Trials
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