Plinabulin

Generic Name
Plinabulin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C19H20N4O2
CAS Number
714272-27-2
Unique Ingredient Identifier
986FY7F8XR
Indication

Investigated for use/treatment in cancer/tumors (unspecified).

Associated Conditions
-
Associated Therapies
-
bigtencrc.org
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BTCRC-LUN17-127

A Big Ten Cancer Research Consortium study on plinabulin combined with nivolumab and ipilimumab for recurrent small cell lung cancer was published in Lung Cancer Journal. The study, BTCRC-LUN17-127, found the combination tolerable at 30 mg/m², though median progression-free survival was 1.6 months, below the target of 3.5 months. Some patients showed prolonged response.
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