Lamotrigine
- Generic Name
- Lamotrigine
- Brand Names
- Lamictal
- Drug Type
- Small Molecule
- Chemical Formula
- C9H7Cl2N5
- CAS Number
- 84057-84-1
- Unique Ingredient Identifier
- U3H27498KS
- Background
Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It is approved for use in more than 30 cou...
- Indication
Lamotrigine is indicated as adjunctive therapy for the following seizure types in patients ≥2 years of age: partial seizures, primary generalized tonic-clonic seizures, and generalized seizures due to Lennox-Gastaut syndrome.
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- Associated Conditions
- Bipolar 1 Disorder, Generalized Tonic-Clonic Seizures, Partial-Onset Seizures, Seizures, Generalized
- Associated Therapies
- Conversion to monotherapy
Resperine, Gabapentin, or Lamotrigine for the Treatment of Cocaine Dependence: 2 - 7
- Conditions
- First Posted Date
- 2001-04-18
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00015106
- Locations
- 🇺🇸
Cincinnati MDRU, Cincinnati, Ohio, United States
Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
- Conditions
- First Posted Date
- 2001-03-15
- Last Posted Date
- 2007-05-04
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 5000
- Registration Number
- NCT00012558
- Locations
- 🇺🇸
Case Western Reserve University, Cleveland, Ohio, United States
🇺🇸University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, United States
🇺🇸University of Pittsburgh, Pittsburgh, Pennsylvania, United States
Does Gabapentin and Lamotriginel Have Significantly Fewer Side-effects While Providing Equal or Better Seizure Control Than the Current Drug Choice, Carbamazepine, for the Treatment of Seizures in the Elderly.
- Conditions
- First Posted Date
- 2001-01-04
- Last Posted Date
- 2023-10-30
- Lead Sponsor
- US Department of Veterans Affairs
- Target Recruit Count
- 720
- Registration Number
- NCT00007670
- Locations
- 🇺🇸
Bronx VA Medical Center, Bronx, New York, United States
🇺🇸Edward Hines Jr. VA Hospital, Hines, Illinois, United States
🇺🇸Birmingham VA Medical Center, Birmingham, Alabama, United States
Neurobiology of Opioid Dependence: 1 - 1
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2015-08-07
- Lead Sponsor
- Yale University
- Registration Number
- NCT00000192
- Locations
- 🇺🇸
VA Connecticut Healthcare System, New Haven, Connecticut, United States
Drug Development Updates
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