Sodium stibogluconate
- Generic Name
- Sodium stibogluconate
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C12H35Na3O26Sb2
- CAS Number
- 16037-91-5
- Unique Ingredient Identifier
- APJ6285Y89
- Background
Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). Widespread resistance has limited the utility of sodium stibogluconate, and in many parts of the world, amphotericin or miltefosine are used instead. It is also being investigated as an anti-tumor agent.
- Indication
For the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
- Associated Conditions
- Leishmaniasis, Mucocutaneous Leishmaniasis, Visceral Leishmaniasis
- Associated Therapies
- -
Efficacy/Safety of Sodium Stibogluconate (SSG) Versus Paromomycin (PM) and SSG/PM Combination to Treat V Leishmaniasis
- Conditions
- Interventions
- First Posted Date
- 2005-11-21
- Last Posted Date
- 2016-03-22
- Lead Sponsor
- Drugs for Neglected Diseases
- Target Recruit Count
- 1142
- Registration Number
- NCT00255567
- Locations
- 🇺🇬
Amudat Hospital, Amudat, Nakipiripirit district, Uganda
🇰🇪KEMRI, Nairobi, Kenya
🇪🇹Arba Minch Hospital, Arba Minch, Ethiopia
Drug Development Updates
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