Dronabinol
- Generic Name
- Dronabinol
- Brand Names
- Marinol, Sativex, Syndros
- Drug Type
- Small Molecule
- Chemical Formula
- C21H30O2
- CAS Number
- 1972-08-3
- Unique Ingredient Identifier
- 7J8897W37S
- Background
Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, which results in the well-known effects of smoking cannabis such as increased ...
- Indication
Dronabinol is indicated for the treatment of anorexia associated with weight loss in patients with AIDS, and nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments.
- Associated Conditions
- Anorexia, Chemotherapy-Induced Nausea and Vomiting
- Associated Therapies
- -
Age-Related Effects of THC
- Conditions
- Interventions
- First Posted Date
- 2020-03-04
- Last Posted Date
- 2023-11-09
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 24
- Registration Number
- NCT04294966
- Locations
- 🇺🇸
University of Chicago Hospital, Chicago, Illinois, United States
🇺🇸University of Chicago, Chicago, Illinois, United States
The Pharmacokinetic and Pharmacodynamic Effects of Oral Cannabidiol (CBD) Under Acute and Chronic Exposure Conditions
- First Posted Date
- 2020-02-25
- Last Posted Date
- 2024-08-07
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 75
- Registration Number
- NCT04283019
- Locations
- 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
Effects of Cannabis on Cognition and Endocannabinoid Levels in Bipolar Disorder Patients and Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2020-01-18
- Last Posted Date
- 2024-05-10
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 19
- Registration Number
- NCT04231643
- Locations
- 🇺🇸
UC San Diego Medical Center, San Diego, California, United States
Nutrition and Pharmacological Algorithm for Oncology Patients Study
- First Posted Date
- 2019-11-07
- Last Posted Date
- 2022-11-16
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 1
- Registration Number
- NCT04155008
- Locations
- 🇺🇸
Montefiore Hospital, Bronx, New York, United States
Behavioral Pharmacology of THC and Alpha-pinene
- First Posted Date
- 2019-10-17
- Last Posted Date
- 2024-05-29
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 33
- Registration Number
- NCT04130633
- Locations
- 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
Effects of Dronabinol in Opioid Maintained Patients
- First Posted Date
- 2019-07-18
- Last Posted Date
- 2024-11-06
- Lead Sponsor
- Yale University
- Target Recruit Count
- 36
- Registration Number
- NCT04025359
- Locations
- 🇺🇸
VA Healthcare System, West Haven, Connecticut, United States
Comparison of Safety, Tolerability and Pharmacokinetics of Medical Grade Cannabis (MGC) Orally Disintegrating Tablets With Buccal Sativex®, in Healthy Adult Volunteers
- Conditions
- Interventions
- First Posted Date
- 2019-05-03
- Last Posted Date
- 2019-07-24
- Lead Sponsor
- One World Cannabis Ltd.
- Target Recruit Count
- 16
- Registration Number
- NCT03936907
- Locations
- 🇮🇱
Tel Aviv Sourasky Medical Center, Tel Aviv, Israel (isr), Israel
The Effect of Tetrahydrocannabinol on Ocular Hemodynamics in Healthy Subjects
- First Posted Date
- 2019-04-08
- Last Posted Date
- 2019-04-10
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 24
- Registration Number
- NCT03907163
- Locations
- 🇦🇹
Department of Clinical Pharmacology, Medical University Vienna, Vienna, Austria
Individual Differences in Drug Response
- Conditions
- Interventions
- First Posted Date
- 2019-01-18
- Last Posted Date
- 2024-07-03
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 60
- Registration Number
- NCT03809546
- Locations
- 🇺🇸
University of Chicago, Chicago, Illinois, United States
Developing a Mobile Method to Measure THC-induced Impairment
- Conditions
- Interventions
- First Posted Date
- 2019-01-15
- Last Posted Date
- 2019-01-15
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 48
- Registration Number
- NCT03804840
- Locations
- 🇺🇸
University of Chicago, Chicago, Illinois, United States
Drug Development Updates
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