MedPath

MK-0482

Generic Name
MK-0482
Drug Type
Biotech

Overview

MK-0482 is a novel humanized IgG4 monoclonal antibody targeting the immunoglobulin-like transcript (ILT) 3.

Background

MK-0482 is a novel humanized IgG4 monoclonal antibody targeting the immunoglobulin-like transcript (ILT) 3.

Indication

No indication information available.

Associated Conditions

No associated conditions information available.

Clinical Trials

A Study to Evaluate MK-0482 for Relapsed/Refractory Acute Myeloid Leukemia (AML) or Chronic Myelomonocytic Leukemia (CMML) (MK-0482-002)
Phase 1
Terminated
Posted: 2021/09/09
Sponsor:Merck Sharp & Dohme ...
ID:NCT05038800
KEYMAKER-U01 Substudy 3: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Participants With Advanced Non-small Cell Lung Cancer (NSCLC), Previously Treated With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Therapy (MK-3475-01C/KEYMAKER-U01C)
Phase 2
Active, not recruiting
Posted: 2019/11/15
Sponsor:Merck Sharp & Dohme ...
ID:NCT04165096
KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)
Phase 2
Recruiting
Posted: 2019/11/15
Sponsor:Merck Sharp & Dohme ...
ID:NCT04165070
KEYMAKER-U01 Substudy 2: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Treatment-naïve Participants With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Positive Advanced Non-small Cell Lung Cancer (NSCLC) (MK-3475-01B/KEYMAKER-U01B)
Phase 2
Active, not recruiting
Posted: 2019/11/15
Sponsor:Merck Sharp & Dohme ...
ID:NCT04165083
A Study of MK-0482 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-0482-001)
Phase 1
Active, not recruiting
Posted: 2019/04/17
Sponsor:Merck Sharp & Dohme ...
ID:NCT03918278

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

No Singapore products found for this drug

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