MedPath

KT-253

Generic Name
KT-253
Brand Names
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Drug Type
Small Molecule
Chemical Formula
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CAS Number
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Unique Ingredient Identifier
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Background

KT-253 is a selective heterobifunctional small molecule degrader of mouse double minute 2 (MDM2).

Associated Conditions
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Associated Therapies
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synapse.patsnap.com
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Lirodegimod - Drug Targets, Indications, Patents

Kymera Therapeutics advances its immunology pipeline with KT-621 (STAT6) Phase 1 trial initiation, expecting data by mid-2025. Sanofi expands KT-474 (IRAK4) Phase 2 trials for HS and AD, aiming for completion by mid-2026. KT-295 (TYK2) selected for Phase 1 trials in 2025. Company shifts focus to immunology, with $911M cash extending runway to mid-2027.
finance.yahoo.com
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Kymera Therapeutics Inc (KYMR) (Q1 2024) Earnings Call Transcript Highlights

Kymera Therapeutics reported $10.3M revenue, $745M cash balance, and a financial runway into 2027. Progressing KT-474 into Phase 2 trials, it faces competition and clinical trial risks. Encouraging data presented at medical meetings, with a focus on developing effective, safe oral treatments.
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