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EMA Product

Ceplene

Product approved by European Medicines Agency (EU)

Basic Information

Ceplene

Regulatory Information

EMEA/H/C/000796

Authorised

October 7, 2008

12

April 19, 2023

Company Information

France

Laboratoires Delbert 49 Rue Rouelle 75015 Paris

Laboratoires Delbert SAS

Drug Classification

Additional MonitoringExceptional Circumstances

Active Substances Detail

Detailed Information

Therapeutic Indication

### Therapeutic indication Ceplene maintenance therapy is indicated for adult patients with acute myeloid leukaemia in first remission concomitantly treated with interleukin-2 (IL-2). The efficacy of Ceplene has not been fully demonstrated in patients older than age 60.

Overview Summary

Ceplene is a medicine used in combination with interleukin-2 (a cancer medicine) as maintenance treatment in adults with acute myeloid leukaemia (AML), a type of cancer affecting the white blood cells. It is used during the patients’ first ‘remission’ (a period without symptoms of the disease after the first course of treatment). AML is rare, and Ceplene was designated an ‘orphan medicine’ (a medicine used in rare diseases) on 11 April 2005. Ceplene contains the active substance histamine dihydrochloride.

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