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EMA Product

Trisenox

Product approved by European Medicines Agency (EU)

Basic Information

Trisenox

Regulatory Information

EMEA/H/C/000388

Authorised

March 5, 2002

31

May 25, 2023

Company Information

Netherlands

Swensweg 5 2031 GA Haarlem

Teva Pharma B.V.

Active Substances Detail

Detailed Information

Therapeutic Indication

### Therapeutic indication Trisenox is indicated for induction of remission, and consolidation in adult patients with: - Newly diagnosed low-to-intermediate risk acute promyelocytic leukaemia (APL) (white blood cell count, ? 10 x 103/µl) in combination with all?trans?retinoic acid (ATRA) - Relapsed/refractory acute promyelocytic leukaemia (APL) (previous treatment should have included a retinoid and chemotherapy) characterised by the presence of the t(15;17) translocation and/or the presence of the Pro-Myelocytic Leukaemia/Retinoic-Acid-Receptor-alpha (PML/RAR-alpha) gene. The response rate of other acute myelogenous leukaemia subtypes to arsenic trioxide has not been examined.

Overview Summary

This is a summary of the European public assessment report (EPAR) for Trisenox. It explains how the Agency assessed the medicine to recommend its authorisation in the EU and its conditions of use. It is not intended to provide practical advice on how to use Trisenox. For practical information about using Trisenox, patients should read the package leaflet or contact their doctor or pharmacist.

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