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EMA Product

Nityr

Product approved by European Medicines Agency (EU)

Basic Information

Nityr

Regulatory Information

EMEA/H/C/004582

Authorised

July 26, 2018

May 31, 2018

5

June 5, 2023

Company Information

Cycle Pharmaceuticals (Europe) Ltd,70 Sir John Rogerson's Quay,Dublin 2,Ireland

Ireland

70 Sir John Rogerson's Quay Dublin 2

cycle pharmaceuticals (europe) ltd

Drug Classification

Generic Medicine

Active Ingredients

Active Substances Detail

Detailed Information

Therapeutic Indication

### Therapeutic indication Treatment of adult and paediatric patients with confirmed diagnosis of hereditary tyrosinemia type 1 (HT-1) in combination with dietary restriction of tyrosine and phenylalanine.

Overview Summary

Nityr is a medicine used to treat hereditary tyrosinaemia type 1 (HT-1). This is a rare disease in which the body is unable to completely break down the amino acid tyrosine and, as a result, harmful substances are formed, causing serious liver problems and liver cancer. Nityr is used together with a diet that restricts the intake of the amino acids tyrosine and phenylalanine. These amino acids are normally found in proteins in foods and drinks. Nityr contains the active substance nitisinone and is a ‘generic medicine’. This means that Nityr contains the same active substance and works in the same way as a ‘reference medicine’ already authorised in the EU called Orfadin.

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