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EMA Product

Trepulmix

Product approved by European Medicines Agency (EU)

Basic Information

Trepulmix

Regulatory Information

EMEA/H/C/005207

Authorised

April 3, 2020

January 30, 2020

7

May 17, 2024

Company Information

Luxembourg

7, Fausermillen 6689 Mertert

SciPharm SARL

Drug Classification

Orphan Medicine

Active Substances Detail

Detailed Information

Therapeutic Indication

### Therapeutic indication Treatment of adult patients with WHO Functional Class (FC) III or IV and: - inoperable chronic thromboembolic pulmonary hypertension (CTEPH), or - persistent or recurrent CTEPH after surgical treatment to improve exercise capacity.

Overview Summary

Trepulmix is a medicine for use in the treatment of chronic thromboembolic pulmonary hypertension (CTEPH), a condition linked with high blood pressure in the lungs caused by blood clots. It can be used to improve the capacity for physical activity in patients: - who cannot have an operation for treating the condition; - whose condition remains or continues to return after an operation to treat it. CTEPH is rare, and [Trepulmix was designated an ‘orphan medicine’](/en/medicines/human/orphan-designations/eu-3-13-1103) (a medicine used in rare diseases) on 8 February 2013. Trepulmix is a ‘hybrid medicine’. This means that it is similar to a ‘reference medicine’ containing the same active substance, but it is used for treating a different form of pulmonary hypertension. The reference medicine for Trepulmix is Remodulin. Trepulmix contains the active substance treprostinil.

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