Basic Information
PENICILLIN G SODIUM SANDOZ 5,000,000 IU/VIAL
INJECTION, POWDER, FOR SOLUTION
Regulatory Information
SIN00682P
May 4, 1988
Prescription Only
Therapeutic
INTRAVENOUS, INTRAMUSCULAR
August 10, 2023
June 3, 2025
XJ01CE01
Company Information
Active Ingredients
Strength: 5 mil iu/vial
Detailed Information
Contraindications
**4.3 Contraindications** - Hypersensitivity to the active substance - History of hypersensitivity to penicillin - History of a severe immediate hypersensitivity reaction (e.g. anaphylaxis) to another beta-lactam agent (e.g. cephalosporin, carbapenem or monobactam)
Indication Information
**4.1 Therapeutic indications** Penicillin G Sodium is indicated for the treatment of the following infections in adults, adolescents, children, newborn infants and pre-term infants, caused by penicillin-sensitive pathogens (see section 5.1 – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_): - septicemia - skin and wound infections - diphtheria (in addition to antitoxin) - community acquired pneumonia - empyema - erysipelas - bacterial endocarditis - peritonitis - meningitis - brain abscesses - osteomyelitis - infections of the genital tract caused by fusobacteria. Penicillin G Sodium is also used for the treatment of the following specific infections: - anthrax - tetanus - listeriosis - pasteurellosis - rat bite fever - fusospirochetosis - actinomycosis Furthermore, Penicillin G Sodium is also used for complications in gonorrhea and syphilis (e.g. gonorrheal endocarditis or arthritis, congenital syphilis). However, in uncomplicated cases, preference should be given to depot penicillins. Penicillin G Sodium is not indicated for the treatment of syphilis during pregnancy. Penicillin G Sodium is also used in Lyme borreliosis from the second stage of the disease onwards (meningopolyneuritis Garin-Bujadoux-Bannwarth, acrodermatitis chronica atrophicans, Lyme arthritis, Lyme carditis) if oral penicillin therapy is no longer indicated. During pregnancy, high-dose parenteral Penicillin G Sodium administration is recommended from the second stage of Lyme disease onwards to prevent diaplacental infection. The generally acknowledged guidelines for the appropriate use of antibacterial agents should be considered when using Penicillin G Sodium.