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HSA Product

UBRETID TABLET 5 mg

Product approved by Health Sciences Authority (SG)

Basic Information

UBRETID TABLET 5 mg

TABLET

Regulatory Information

SIN02915P

May 22, 1989

Prescription Only

Therapeutic

ORAL

August 10, 2023

June 4, 2025

XN07AA03

Company Information

Globopharm

CELLTRION HEALTHCARE SINGAPORE PRIVATE LIMITED

CELLTRION HEALTHCARE SINGAPORE PRIVATE LIMITED

Active Ingredients

DISTIGMINE BROMIDE

Strength: 5 mg

Detailed Information

Contraindications

**Contraindications** UBRETID® must not be used in: Hypersensitivity to the active substance or to any of the excipients as well as bromine allergy, severe vagotonia (dominance of the parasympathetic part of the autonomic-vegetative-nervous system) accompanied by low blood pressure, slow heart rate, hyperacidity, hyperperistalsis of intestine and stomach, increased salivation, peripheral circulatory disturbances, mechanical obstruction to urinary outflow, obstructive ileus, stenosis or spasms in the intestinal tract, in the biliary ducts and urinary passages, gastric ulcers, enteritis; very low blood pressure, increased muscular tone, muscular spasm (tetany), falling sickness (epilepsy), shaking palsy (Parkinson’s disease), postoperative shock and circulatory crises; non-treated cardiac insufficiency, cardiac infarction, congestive heart failure, recent myocardial infarction, cardiac arrhythmias, in particular bradycardia and AV block, bronchial asthma, Iritis, myotonia, and thyrotoxicosis.

Indication Information

**Indications** Functional insufficiency of the vesical sphincteral apparatus Hypotonia of the urinary bladder Chronic hypotonic constipation and megacolon In various neurological indications (peripheral paralyses of the striated muscles, myasthenia gravis pseudoparalytica) a functional improvement can be obtained.

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