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HSA Product

SIVEXTRO FILM-COATED TABLET 200MG

Product approved by Health Sciences Authority (SG)

Basic Information

SIVEXTRO FILM-COATED TABLET 200MG

TABLET, FILM COATED

Regulatory Information

SIN14850P

September 16, 2015

Prescription Only

Therapeutic

ORAL

August 10, 2023

May 30, 2025

XJ01XX11

Company Information

Patheon Inc.

MSD PHARMA (SINGAPORE) PTE. LTD.

MSD PHARMA (SINGAPORE) PTE. LTD.

Active Ingredients

Detailed Information

Contraindications

**4 CONTRAINDICATIONS** SIVEXTRO is contraindicated in patients with known hypersensitivity to the active substance or to any of the excipients in the drug product.

Indication Information

**1 INDICATIONS AND USAGE** **1.1 Acute Bacterial Skin and Skin Structure Infections** SIVEXTRO is an oxazolidinone-class antibacterial indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible isolates of the following Gram-positive microorganisms: _Staphylococcus aureus_ (including methicillin-resistant \[MRSA\] and methicillin-susceptible \[MSSA\] isolates), _Streptococcus pyogenes_, _Streptococcus agalactiae_, _Streptococcus anginosus_ Group (including _Streptococcus anginosus_, _Streptococcus intermedius_, and _Streptococcus constellatus_), and _Enterococcus faecalis_. **1.2 Usage** To reduce the development of drug-resistant bacteria and maintain the effectiveness of SIVEXTRO and other antibacterial drugs, SIVEXTRO should be used only to treat ABSSSI that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

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