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HSA Product

CoPlavix Film-Coated Tablet 75 mg/100 mg

Product approved by Health Sciences Authority (SG)

Basic Information

CoPlavix Film-Coated Tablet 75 mg/100 mg

TABLET, FILM COATED

Regulatory Information

SIN13514P

August 8, 2008

Prescription Only

Therapeutic

ORAL

August 10, 2023

May 30, 2025

XB01AC30

Company Information

SANOFI-AVENTIS SINGAPORE PTE. LTD.

SANOFI-AVENTIS SINGAPORE PTE. LTD.

Active Ingredients

Detailed Information

Contraindications

**Contraindications** Due to the presence of both components of the product, CoPlavix is contraindicated in case of: - Hypersensitivity to either of the active substances or the excipients of the medicinal product. - severe liver impairment. - active pathological bleeding such as peptic ulcer or intracranial haemorrhage. In addition, due to the presence of ASA, its use is also contraindicated: - In patients with known allergy to non-steroidal anti-inflammatory drugs (NSAIDs) products and in patients with the syndrome of asthma, rhinitis, and nasal polyps. Patients with pre-existing mastocytosis, in whom the use of ASA may induce severe hypersensitivity reactions (including circulatory shock with flushing, hypotension, tachycardia and vomiting). - In patients with severe renal impairment (CrCL < 30 ml/min). - In patients with active or history of peptic ulceration, haemophilia and other bleeding disorders. - Third trimester of pregnancy (see section _“Pregnancy and lactation”_ – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_).

Indication Information

**Therapeutic indications** CoPlavix is indicated for the secondary prevention of atherothrombotic events in patients suffering from acute coronary syndrome: - **Non-ST segment** elevation acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction). - ST segment elevation acute myocardial infarction in medically treated patients eligible for thrombolytic therapy For further information please refer to section _“Pharmacodynamic properties”_ – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_.

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