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HSA Product

Rebif Solution for Injection in Cartridge 44mcg/0.5ml

Product approved by Health Sciences Authority (SG)

Basic Information

Rebif Solution for Injection in Cartridge 44mcg/0.5ml

INJECTION, SOLUTION

Regulatory Information

SIN13975P

June 17, 2011

Prescription Only

Therapeutic

SUBCUTANEOUS

August 10, 2023

June 3, 2025

XL03AB07

Company Information

MERCK PTE. LTD.

MERCK PTE. LTD.

Active Ingredients

Interferon beta-1a

Strength: 44mcg/0.5ml

Detailed Information

Contraindications

**4.3 Contraindications** - Hypersensitivity to natural or recombinant interferon-β, or to any excipients. - Current severe depression and/or suicidal ideation (see sections 4.4 and 4.8 – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_).

Indication Information

**4.1 Therapeutic indications** Rebif is indicated for the treatment of - patients with a single demyelinating event with an active inflammatory process, if alternative diagnoses have been excluded, and if they are determined to be at high risk of developing relapsing multiple sclerosis (see section 5.1 – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_). - patients with relapsing multiple sclerosis. In clinical trials, this was characterised by two or more acute exacerbations in the previous two years (see section 5.1 – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_). Efficacy has not been demonstrated in patients with secondary progressive multiple sclerosis without ongoing relapse activity (see section 5.1 – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_).

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