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HSA Product

SPRAZOLE-20 ESOMEPRAZOLE GASTRO RESISTANT 20 MG TABLETS

Product approved by Health Sciences Authority (SG)

Basic Information

SPRAZOLE-20 ESOMEPRAZOLE GASTRO RESISTANT 20 MG TABLETS

TABLET, DELAYED RELEASE

Regulatory Information

SIN16686P

February 8, 2023

Prescription Only

Therapeutic

ORAL

August 10, 2023

June 3, 2025

XA02BC05

Company Information

Lee Pharma Limited

MEDICELL PHARMACEUTICAL (S) PTE. LTD.

MEDICELL PHARMACEUTICAL (S) PTE. LTD.

Active Ingredients

Detailed Information

Contraindications

**4.3 Contraindications** Known hypersensitivity to esomeprazole, substituted benzimidazoles or any other constituents of the formulation.

Indication Information

**4.1 Therapeutic indications** Esomeprazole tablets are indicated for: **Gastroesophageal Reflux Disease (GERD)** - Treatment of erosive reflux esophagitis. - Long-term management of patients with healed esophagitis to prevent relapse. - Symptomatic treatment of gastroesophageal reflux disease (GERD). **In combination with an appropriate antibacterial therapeutic regimen for the eradication of Helicobacter pylori and** - Healing of _Helicobacter pylori_ associated duodenal ulcer and - Prevention of relapse of peptic ulcers in patients with Helicobacter pylori associated ulcers. **Patients requiring continued NSAID therapy** - Healing of gastric ulcers associated with NSAID therapy. - Prevention of gastric and duodenal ulcers associated with NSAID therapy in patients at risk. Patients are considered to be at risk due to their age (≥ 60) and/or documented history of gastric and/or duodenal ulcers. Controlled studies do not extend beyond 6 months. **Patients requiring continued low dose aspirin (75–325 mg) therapy** - Prevention of gastric and/or duodenal ulcers associated with low dose aspirin therapy, in patients at risk. **Prevention of rebleeding of gastric or duodenal ulcers following treatment with esomeprazole IV solution by intravenous infusion.** **Treatment of Zollinger Ellison Syndrome**

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