Pulmonary Vein Isolation vs Sham Intervention in Symptomatic Atrial Fibrillation
Pulmonary vein isolation significantly reduced atrial fibrillation burden at 6 months, with substantial improvements in symptoms and quality of life compared to a sham procedure, indicating no placebo effect.
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Pulmonary vein isolation (PVI) significantly improved atrial fibrillation burden and quality of life at 6 months compared to a sham intervention, according to a sham-controlled trial. The study, SHAM-PVI, conducted at two U.K. centers, showed no clinically relevant placebo effect, confirming PVI's efficacy.
Pulmonary vein isolation significantly reduced atrial fibrillation burden at 6 months, with substantial improvements in symptoms and quality of life compared to a sham procedure, indicating no placebo effect.
Pulmonary vein isolation significantly reduced atrial fibrillation burden by 60.31% vs. 35.0% with sham at 6 months, improving quality of life more than a sham procedure.