Oncolytics Biotech Inc. announced it will present new clinical data from its GOBLET study at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, scheduled for May 30-June 3, 2025, in Chicago. The presentation will focus on Cohort 1 results demonstrating the anti-tumor activity of pelareorep in patients with pancreatic ductal adenocarcinoma (PDAC).
Clinical Significance for Pancreatic Cancer
PDAC represents the most common form of pancreatic cancer and remains one of the most challenging malignancies to treat. The disease is characterized by its aggressive nature, poor prognosis, and extremely limited therapeutic options available to patients. Current treatment approaches have shown minimal impact on overall survival, creating a critical unmet medical need in oncology.
The upcoming ASCO presentation will provide insights into pelareorep's potential as a novel therapeutic approach for this difficult-to-treat cancer. Pelareorep is an oncolytic virus therapy designed to selectively target and destroy cancer cells while potentially stimulating an immune response against tumors.
GOBLET Study Overview
The GOBLET study represents a key clinical trial in Oncolytics Biotech's development program for pelareorep. Cohort 1 data will offer the first glimpse into the drug's efficacy and safety profile specifically in PDAC patients, providing crucial information for the continued development of this investigational therapy.
The timing of this data presentation at ASCO 2025 positions Oncolytics to share its findings with the global oncology community at one of the most prestigious cancer research conferences worldwide.
Market Response
Following the announcement, Oncolytics Biotech shares (TSX: ONC) declined $0.02 to close at $0.76, reflecting a modest market reaction to the news. The company's stock performance will likely be influenced by the actual data results when they are presented at the conference.
The presentation at ASCO 2025 will be closely watched by investors, clinicians, and researchers interested in novel approaches to treating pancreatic cancer, particularly given the significant challenges associated with current treatment paradigms for this aggressive malignancy.
