Central Florida Kidney Specialists (CFKS), a leading institution in nephrology clinical research, has announced a strategic partnership with ClinTrial Research (CTR), a technology-focused site management organization. The collaboration, announced on April 29, 2025, aims to enhance clinical trial management and expand access to innovative therapies for patients with kidney-related conditions.
Founded in 1971, CFKS stands as the oldest and largest independent nephrology practice in the Southeastern United States. Its research division, NCCF.R, has established itself as an internationally recognized center for nephrology clinical research, providing access to experimental therapies for patients with kidney disorders.
Transformative Impact of Clinical Research
Dr. Arvind Madan, Founder and President of NCCF.R and current President of the Florida Society of Nephrology, emphasized the life-changing potential of clinical trials through a compelling patient case study.
"The greatest impact I have seen in a clinical trial was with a patient whose kidney function had dropped to less than 25% and they were giving up completely on treatments," Dr. Madan recounted. "A new clinical trial at our practice offered a glimmer of hope. The patient enrolled, and within 3 months their kidney function recovered to almost normal. It was a remarkable turnaround."
This dramatic improvement illustrates the potential benefits of experimental therapies in nephrology, particularly for patients who have exhausted conventional treatment options.
Expanding Access to Cutting-Edge Therapies
The partnership will focus on providing patients with opportunities to receive the latest therapeutic options for rare kidney diseases, chronic kidney disease, and cardio-metabolic conditions. By combining CFKS's clinical expertise with CTR's technological capabilities, the collaboration aims to enhance patient recruitment, improve trial efficiency, and ultimately accelerate the development of new treatments.
"The CFKS team are excited for this new chapter in our research group," Dr. Madan stated. "The ability to bring patients a chance to receive the latest therapeutic options in rare kidney diseases, chronic kidney disease and cardio-metabolic conditions is exhilarating."
Technology-Driven Clinical Trial Management
ClinTrial Research, launched in 2024, brings innovative approaches to clinical trial management. The company employs an industry-leading AI patient matching tool called Trially, which helps identify suitable candidates for clinical trials with greater precision and efficiency.
A distinctive feature of CTR's operational model is the embedding of research employees directly within clinical practice locations. This approach facilitates stronger relationships between research staff, healthcare providers, and patients, potentially improving trial adherence and outcomes.
Patient-Centered Approach
Wendy Tomlinson, Chief Operating Officer at CTR, highlighted the company's commitment to enhancing the patient experience throughout the clinical trial process.
"The combination of AI technology, physician excellence and a keen focus on positive patient experiences whilst achieving or exceeding Sponsor targets makes this partnership a new high-water mark for the industry," Tomlinson said. "We are thrilled to be partnering with CFKS. Dr. Madan and his team have contributed significantly to a range of scientific publications on the global stage."
Addressing Unmet Needs in Kidney Disease
Kidney diseases represent a significant health burden globally. Chronic kidney disease (CKD) affects approximately 15% of US adults, with many progressing to end-stage renal disease requiring dialysis or transplantation. Despite advances in standard care, there remains a substantial need for novel therapies that can slow disease progression, improve quality of life, and potentially restore kidney function.
The CFKS-CTR partnership represents a step toward addressing these unmet needs by facilitating access to experimental treatments and accelerating the clinical development process. By combining clinical expertise with technological innovation, the collaboration aims to improve both the efficiency of clinical trials and the experiences of participating patients.
As the partnership develops, it may serve as a model for integrating advanced technology into clinical research while maintaining a strong focus on patient care and scientific rigor in the field of nephrology.
