PRINCE Trial Highlights Early Detection of Prostate Cancer Progression with PSMA PET-CT
Michael Hofman discusses developing new PSMA PET-CT criteria for prostate cancer progression evaluation, aiming to replace PCWG3 guidelines. Using PRINCE trial data, his team shows high inter-reader agreement and earlier progression detection with PSMA PET-CT, correlating well with overall survival. Hofman emphasizes the need for contrast-enhanced CT in PSMA PET-CT protocols and plans further validation across multiple trials.
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Michael Hofman discusses developing new PSMA PET-CT criteria for prostate cancer progression evaluation, aiming to replace PCWG3 guidelines. Using PRINCE trial data, his team shows high inter-reader agreement and earlier progression detection with PSMA PET-CT, correlating well with overall survival. Hofman emphasizes the need for contrast-enhanced CT in PSMA PET-CT protocols and plans further validation across multiple trials.