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New Zealand Expands Access to Pembrolizumab and Nivolumab for Multiple Cancers

• Pembrolizumab (Keytruda) will be funded from October 1, 2024, for advanced triple-negative breast cancer, head and neck cancer, colorectal cancer, bladder cancer, and Hodgkin lymphoma in New Zealand. • Nivolumab (Opdivo) will be funded from November 1, 2024, for eligible patients with kidney cancer, offering a new treatment option for this patient population. • The expanded access is expected to benefit approximately 1,000 people in the first year, increasing to 4,500 over five years, improving survival and quality of life. • Funding has also been approved for posaconazole and voriconazole for individuals at high risk of invasive fungal infections, such as those undergoing cancer treatment or organ transplants.

New Zealand's Pharmaceutical Management Agency (Pharmac) has announced the expansion of access to pembrolizumab and nivolumab for several types of cancer, following a boost in government funding. This decision marks a significant step forward in cancer treatment accessibility in the country, offering new hope for patients with advanced malignancies.

Pembrolizumab (Keytruda) Access Widened

From October 1, 2024, pembrolizumab, marketed as Keytruda, will be funded for eligible individuals diagnosed with advanced triple-negative breast cancer, head and neck cancer, colorectal cancer, bladder cancer, and Hodgkin lymphoma. This immunotherapy drug has shown promising results in clinical trials, improving survival rates and quality of life for patients with these aggressive cancers.
Ah-Leen Rayner, Chief Executive of the Breast Cancer Foundation NZ, hailed the decision, stating, "Keytruda is a breakthrough drug that can help patients live significantly longer and healthier lives. It’s recognised internationally as the best way to treat this form of the disease."

Nivolumab (Opdivo) Funding Approved

In addition to pembrolizumab, nivolumab (Opdivo) will be funded from November 1, 2024, for eligible patients with kidney cancer. This provides another valuable treatment option for individuals battling this challenging disease.

Impact and Patient Benefits

Pharmac estimates that approximately 1,000 additional people will gain access to these treatments in the first year of funding, with the number increasing to 4,500 over five years. Geraldine MacGibbon, Pharmac’s Director of Pharmaceuticals, emphasized the impact of this decision: "Access to these medicines will slow down the progression of these cancers and improve survival so that people have more valuable time with their whānau and friends."
Liam Willis, Executive Officer of the Gut Foundation, expressed his gratitude for the widened access to pembrolizumab for microsatellite instability high or deficient mismatch repair (MSI-H/dMMR) colorectal cancer (CRC) patients: "This group of patients hasn't had any new treatments funded for over 20 years and we are heartened to see this option become available... As a result, this decision means more people will get access to this treatment and those currently self-funding will be able to have that financial burden removed."

Additional Medicine Access

Pharmac has also approved funding for widened access to the medicines posaconazole and voriconazole from 1 October for people at high risk of invasive fungal infections, such as people undergoing cancer treatment or organ transplants.
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Reference News

[2]
First Cancer Medicine Decision Following Pharmac Funding Boost | Scoop News
scoop.co.nz · Sep 15, 2024

Pharmac widens access to pembrolizumab (Keytruda) for advanced triple-negative breast cancer, head and neck cancer, colo...

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