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25 Years of CGM Innovation: Major Advances Mark 2024 as Breakthrough Year for Glucose Monitoring

  • The continuous glucose monitoring field celebrates its 25th anniversary since the first FDA approval in 1999, with Medtronic's MiniMed leading the way and receiving approval for their new Simplera CGM in 2024.

  • Dexcom achieves a significant milestone with Stelo, the first FDA-approved over-the-counter CGM, while expanding integration capabilities with insulin pumps and wearable devices like the Oura Ring.

  • Abbott and Senseonics make remarkable progress with Abbott's Libre 3 plus offering 15-day wear with real-time data, and Senseonics receiving approval for the groundbreaking 365-day implantable Eversense system.

The continuous glucose monitoring (CGM) landscape has transformed dramatically since its inception, marking 2024 as a pivotal year for diabetes care technology. As the industry celebrates 25 years since the first FDA approval, major manufacturers are introducing groundbreaking innovations that are reshaping diabetes management.

Historic Evolution and Current Innovations

Medtronic, which acquired the pioneering MiniMed technology after its initial 1999 FDA approval, continues to lead innovation in the CGM space. The company's recent approval of the Simplera CGM system represents their latest advancement in making glucose monitoring more user-friendly and accurate.
Dexcom has made remarkable strides since introducing their STS sensor in 2006. Their current G7 model exemplifies the company's commitment to technological advancement, offering enhanced integration capabilities with multiple insulin delivery systems, including the OmniPod 5, T:slim X2, and the Islet. In a groundbreaking development, Dexcom's Stelo has become the first FDA-approved over-the-counter CGM, marking a significant step toward broader accessibility of glucose monitoring technology.

Advanced Features and Integration

Abbott's journey from the Navigator to the current Libre 3 plus system showcases the evolution of CGM technology. The Libre 3 plus offers extended 15-day wear capability and real-time data transmission, while the company's collaborations with Tidepool and major insulin pump manufacturers demonstrate their commitment to creating a more connected diabetes care ecosystem. The FDA clearance of Abbott's Lingo and Libre Rio further expands their portfolio of monitoring solutions.

Revolutionary Implantable Technology

Senseonics has revolutionized long-term glucose monitoring with their Eversense CGM system, the only FDA-approved implantable CGM device. The company's latest achievement – the approval of their 365-day wear system in 2024 – represents a significant advancement from their original 90-day sensor. This development points toward future possibilities, including the potential elimination of external transmitters for a fully implantable design.

Impact on Diabetes Care

These technological advances are fundamentally changing the landscape of diabetes management. The integration capabilities, extended wear times, and improved accuracy of modern CGM systems provide healthcare providers and patients with more comprehensive and convenient options for monitoring glucose levels. The introduction of over-the-counter options and longer-lasting implantable devices particularly marks a new era in accessibility and ease of use in diabetes care.
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Reference News

[1]
Diabetes Dialogue: Celebrating 2024 - The Year of the Continuous Glucose Monitor
hcplive.com · Dec 16, 2024

This episode of Diabetes Dialogue recaps CGM updates from Medtronic, Dexcom, Abbott, and Senseonics, marking the 25th an...

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