PhotoPharmics Reaches 50% Enrollment Milestone in Phase 3 Trial Testing Light Therapy for Parkinson's Disease
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PhotoPharmics has enrolled 150 participants in its Light for PD Phase 3 clinical trial, evaluating specialized phototherapy for both motor and non-motor symptoms of Parkinson's disease.
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Building on promising Phase 2 results, the innovative light therapy device aims to improve patients' quality of life by targeting circadian function and neurological health.
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The study, led by Dr. Ray Dorsey at the University of Rochester, focuses on addressing often-overlooked non-motor symptoms that significantly impact daily life but have limited treatment options.
PhotoPharmics has achieved a significant milestone in its pioneering Phase 3 clinical trial investigating specialized light therapy for Parkinson's disease, announcing 50% enrollment with 150 participants now registered in the Light for PD study. The trial evaluates a novel therapeutic approach designed to complement existing treatments by addressing both motor and non-motor symptoms of the disease.
The study builds upon encouraging Phase 2 results that demonstrated notable improvements in patients' quality of life. The specialized phototherapy device works by supporting circadian function and neurological health, showing promise in enhancing sleep quality, cognitive function, and mood regulation. Additionally, preliminary data suggested potential benefits for traditional motor symptoms such as tremor and slowness of movement.
Dr. Ray Dorsey, professor of neurology at the University of Rochester and principal investigator for the study, emphasized the trial's significance: "This trial is important because it addresses the often-overlooked aspects of Parkinson's disease—non-motor symptoms that severely impact daily life but have few effective treatments. By targeting circadian disruption, which plays a significant role in these symptoms, this therapy could provide much-needed relief to millions of people with Parkinson's."
Unlike conventional Parkinson's medications that primarily target tremors and rigidity, PhotoPharmics' light therapy is designed to work synergistically with standard treatments. The approach aims to enhance overall patient well-being through multiple pathways, potentially improving both motor and non-motor symptoms.
"Our goal is to fundamentally change how we treat Parkinson's disease by providing a breakthrough therapy that addresses not just the visible symptoms but also the hidden burdens of the disease," stated Kent Savage, CEO of PhotoPharmics. He noted that Phase 2 research demonstrated the potential for meaningful, lasting benefits for patients.
The Light for PD trial continues to recruit participants, with researchers seeking to complete enrollment for the remaining 150 positions. The study represents a significant step forward in exploring non-invasive treatment options for Parkinson's disease, potentially offering a new therapeutic modality that could address currently underserved aspects of patient care.
Interested individuals diagnosed with Parkinson's disease can learn more about participation opportunities through the study's dedicated website at lightforpd.com.

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[1]
Photopharmics Achieves 50% Enrollment In Pioneering Phase 3 Parkinson's Trial
menafn.com · Feb 7, 2025
[2]
PhotoPharmics Advances Parkinson's Care with 200 Enrolled in Remote Light Therapy Study
techbuzz.news · Apr 9, 2025