Researchers at the University of Arizona are pioneering a novel approach to combat chronic insomnia using targeted magnetic pulses. The team, led by Dr. William “Scott” Killgore, is developing a handheld device designed to disrupt overactivity in the brain's default mode network (DMN), which is often implicated in racing thoughts and sleeplessness. With a $3 million grant from the Department of Defense, the study primarily aims to address the high prevalence of insomnia among military personnel, where it affects approximately 85% of service members.
Silencing the Default Mode Network
The core of insomnia often lies in the inability to quiet the mind. "Many people with insomnia describe being unable to 'turn off' their thoughts when trying to fall asleep," explains Killgore. The DMN, which becomes hyperactive during rest, is believed to be a key contributor to this mental chatter. The device delivers rapid, repetitive magnetic bursts to specific brain regions in just 40 seconds, effectively silencing the DMN and promoting relaxation.
Promising Early Results
Preliminary studies have demonstrated promising results, with participants reporting improved sleep after a single session of continuous theta burst stimulation. The team is now conducting a more extensive three-year study involving 120 participants with chronic insomnia to validate these findings and assess long-term efficacy.
A Non-Invasive Alternative
What sets this approach apart is its non-invasive nature. Unlike traditional sleeping pills, which can have significant side effects, the magnetic stimulation method is brief and well-tolerated. Participants are monitored using advanced sleep trackers and portable brain wave monitors to evaluate both short-term and sustained improvements. Dr. Jordan Karp, department chair, notes that this research could represent "an important discovery for sleep science," offering "a tangible, drug-free treatment option for those grappling with chronic insomnia."
Addressing Military Needs
Two active-duty military consultants with personal experience of sleep disorders are actively involved in shaping the study, ensuring that the research directly addresses the specific needs of service members. The ultimate goal is to develop a sustainable solution that can be seamlessly integrated into military healthcare systems, providing lasting relief from insomnia and improving overall well-being.