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Abemaciclib, a potent cyclin-dependent kinase 4 and 6 inhibitor, for ...

CDK 4/6 inhibitors, including abemaciclib, offer new treatments for ER+/HER2- advanced breast cancer. Abemaciclib differs in dosing and side effects but shows similar clinical benefits. Its major impact may be in adjuvant therapy, pending MONARCH-E trial results. Biomarker research could identify tumors most responsive to abemaciclib.


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Abemaciclib, a potent cyclin-dependent kinase 4 and 6 inhibitor, for ...

CDK 4/6 inhibitors, including abemaciclib, offer new treatments for ER+/HER2- advanced breast cancer. Abemaciclib differs in dosing and side effects but shows similar clinical benefits. Its major impact may be in adjuvant therapy, pending MONARCH-E trial results. Biomarker research could identify tumors most responsive to abemaciclib.

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