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UAB Launches Clinical Trial Evaluating Novel Therapy for Type 2 Diabetes

• The University of Alabama at Birmingham (UAB) is conducting a clinical trial, TRANSCEND-T2D-2, to assess a new investigational medicine for type 2 diabetes. • The study aims to determine the efficacy of the investigational medicine in managing blood glucose levels and weight compared to existing treatments. • Eligible participants include adults aged 18 or older with type 2 diabetes, a BMI of 25 or higher, and HbA1c levels between 7.0% and 10.5%. • The trial requires participants to have been taking at least 1500mg of metformin daily for a minimum of three months, with or without an SGLT2i.

The University of Alabama at Birmingham (UAB) has initiated the TRANSCEND-T2D-2 clinical trial to investigate a novel therapeutic approach for managing type 2 diabetes. This study seeks to evaluate the effectiveness of an investigational medicine in improving blood glucose control and promoting weight management in adults diagnosed with type 2 diabetes.
The clinical trial compares the investigational medicine against existing treatments for type 2 diabetes. Participants meeting specific criteria are being enrolled to determine if the new therapy offers superior glycemic control and weight reduction benefits.

Eligibility Criteria

To participate in the TRANSCEND-T2D-2 study, individuals must meet several inclusion criteria: they must be 18 years of age or older, have a confirmed diagnosis of type 2 diabetes, maintain a Body Mass Index (BMI) of 25 or greater, and exhibit Hemoglobin A1c (HbA1c) levels ranging from 7.0% to 10.5%. Furthermore, eligible participants must have been consistently taking a daily dosage of 1500mg or more of metformin for at least three months, with or without the concurrent use of an SGLT2 inhibitor (SGLT2i).

Study Objectives

The primary objective of the TRANSCEND-T2D-2 trial is to assess the investigational medicine's ability to improve blood glucose levels, as measured by HbA1c, and to facilitate weight management in individuals with type 2 diabetes. Researchers will compare these outcomes against those achieved with currently available treatments, providing insights into the potential advantages of the new therapy.

Contact Information

Individuals interested in learning more about the TRANSCEND-T2D-2 clinical trial or determining their eligibility can contact Tracie Thomas, RN, at 205-996-4015 or via email at tthoma@uab.edu.
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Reference News

[1]
Type 2 Diabetes Study - The Reporter | UAB
uab.edu · Sep 25, 2024

TRANSCEND-T2D-2 study tests an investigational medicine for type 2 diabetes, focusing on blood glucose and weight manage...

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