Glucose-Dependent Insulinotropic Polypeptide Reduces ...
GIP reduces free fatty acid (FFA) release from adipose tissue by inhibiting 11β-HSD1 activity, affecting lipid metabolism. A clinical trial showed GIP lowers circulating FFAs and reduces 11β-HSD1 and ATGL expression in human adipose tissue, indicating GIP's direct, insulin-independent effects on adipose tissue metabolism.
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Glucose-Dependent Insulinotropic Polypeptide Reduces ...
GIP reduces free fatty acid (FFA) release from adipose tissue by inhibiting 11β-HSD1 activity, affecting lipid metabolism. A clinical trial showed GIP lowers circulating FFAs and reduces 11β-HSD1 and ATGL expression in human adipose tissue, indicating GIP's direct, insulin-independent effects on adipose tissue metabolism.