Safety and Efficacy of the Blood-Stage Malaria Vaccine RH5

The clinical trial for the RH5 malaria vaccine, aimed at assessing its safety and efficacy, has been registered under ClinicalTrials.gov ID: NCT05790889. This study has garnered ethical approvals from both the National Ethical Committee of the Ministry of Health in Burkina Faso and the Oxford Tropical Research Ethics Committee in the UK, ensuring that all research adhered to the highest ethical standards. The trial's funding was supported by a consortium of organizations, including the European and Developing Countries Clinical Trials Partnership, the UK Medical Research Council, the National Institute for Health and Care Research Oxford Biomedical Research Centre, the Division of Intramural Research, National Institute of Allergy and Infectious Diseases, the US Agency for International Development, and the Wellcome Trust. This collaborative effort underscores the global commitment to combating malaria through innovative vaccine research.