Ellipsis Health announced the completion of its $45 million Series A funding round, led by Salesforce, Khosla Ventures, and CVS Health Ventures, alongside the launch of Sage, an emotionally intelligent AI Care Manager designed to transform healthcare delivery for high-cost, complex patients. Previous investors including Mitsui Global Investment, Collier, E12, and AME Cloud Ventures also participated in the funding round.
Revolutionary AI Care Management Platform
Sage represents a significant advancement in AI-powered healthcare, specifically targeting patients with complex physical, behavioral, and social needs who drive the majority of healthcare costs. Unlike traditional AI voice assistants, Sage demonstrates emotional intelligence by adjusting its tone and approach based on a patient's emotional state and mental health needs, ensuring higher levels of engagement and behavior change.
The platform leverages Ellipsis Health's proprietary Empathy Engine, built on patented vocal biomarker technology and trained on millions of live clinical patient calls. This foundation enables Sage to provide emotionally intelligent, context-aware support even for the most complex patients.
"The future of healthcare requires AI that can extend human capabilities while preserving the empathy and clinical judgment that defines great care," said Amit Khanna, SVP & GM, Health & Life Sciences at Salesforce. "Ellipsis Health's Sage does exactly that—combining the emotional intelligence learned from millions of real patient conversations with the workflow integration capabilities of Salesforce Health Cloud."
Addressing Critical Healthcare Challenges
The healthcare industry has long relied on phone conversations with clinicians for between-visit care, supporting triage, care coordination, disease management, and case management. However, staffing shortages, burnout, and increasing patient complexity have made it increasingly difficult to scale these programs effectively while maintaining quality.
Hal Paz of Khosla Ventures, a former health system CEO and practicing physician, emphasized the significance of this challenge: "Voice-based care management has become essential, but it's nearly impossible to scale cost-effectively or without significant loss of quality. Sage stands apart by training its AI on real clinical conversations, enabling emotionally intelligent, context-aware support, even for the most complex patients."
Clinical Integration and Workflow Enhancement
Sage integrates seamlessly with existing clinical operations through Salesforce's Health Cloud workflow engine. According to Mainul Mondal, CEO and Founder of Ellipsis Health, "Sage derives the clinical understanding from our experience developing vocal biomarkers in case management conversations and builds an empathetic, longitudinal care journey by leveraging Salesforce's Health Cloud with its clinical partners, which meets the needs of high-risk, high-cost members."
The platform addresses multiple operational challenges simultaneously: alleviating staffing shortages, reducing rising costs, and meeting increasing patient needs while delivering measurable improvements in healthcare operations and patient outcomes.
Strategic Investment and Market Positioning
CVS Health Ventures highlighted the strategic importance of combining conversational and agentic AI to expand healthcare access. "We're excited by the potential of combining conversational and agentic AI to expand access to healthcare services, particularly in areas like care management," said Vijay Patel, VP and Managing Partner of CVS Health Ventures.
Jerry Yang, founding partner of AME Cloud Ventures, noted the company's unique position in the market: "Ellipsis Health is pioneering a new frontier in healthcare where AI delivers intelligent and compassionate support to patients through its AI voice agent, Sage."
Scaling and Future Development
The $45 million funding will accelerate Sage's adoption across healthcare providers, payers, and care management organizations. Ellipsis Health plans to continue expanding its AI capabilities, enhance clinical integrations, and advance its mission of delivering empathetic, AI-driven healthcare at scale.
Mondal emphasized the comprehensive nature of care management: "It is critical to understand that care management is not just about collecting information and performing tasks for the patient, but also listening to them, being supportive as they move through their care journey and understanding what are the most important priorities to them."
The company positions itself as trusted by top-tier healthcare organizations, including leading providers and payers, to deliver AI solutions specifically designed for handling patients with complex needs that represent the highest healthcare costs. This funding validates Ellipsis Health's approach and enables continued scaling to ensure comprehensive, compassionate care delivery.
