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Clinical trials of prucalopride tablets for CIC involved 2530 patients, showing common adverse reactions like headache (19%), abdominal pain (16%), and nausea (14%). Diarrhea onset was early, resolving quickly. Discontinuation due to adverse reactions was 5% for prucalopride vs. 3% for placebo. Cardiovascular safety analysis showed no significant MACE risk increase.


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These highlights do not include all the information needed to use ...

Clinical trials of prucalopride tablets for CIC involved 2530 patients, showing common adverse reactions like headache (19%), abdominal pain (16%), and nausea (14%). Diarrhea onset was early, resolving quickly. Discontinuation due to adverse reactions was 5% for prucalopride vs. 3% for placebo. Cardiovascular safety analysis showed no significant MACE risk increase.

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