Pillar Biosciences Secures $34.5M Funding Round Led by Illumina to Advance NGS Cancer Testing Platform
- Pillar Biosciences, a leader in Decision Medicine™, has completed a $34.5 million funding round featuring strategic investment from Illumina and structured financing from Soleus Capital.
- The funding will support commercial expansion including increased headcount and infrastructure to advance biopharma partnerships and broaden adoption of distributable clinical testing kits.
- Illumina's investment reinforces its strategic partnership with Pillar, which includes previous agreements from 2017 and 2023, to provide expanded NGS solutions for precision oncology.
- Pillar's proprietary SLIMamp® and PiVAT® technologies enable rapid, cost-effective genomic profiling of tumors, helping laboratories streamline molecular testing platforms for faster results.
Pillar Biosciences, Inc., a Massachusetts-based company specializing in next-generation sequencing (NGS) testing technology for cancer diagnostics, has successfully closed a $34.5 million funding round. The financing includes a strategic investment from genomics giant Illumina, structured financing from Soleus Capital, and additional investments from existing investors.
The funding announcement comes as Pillar continues to establish itself as a leader in what it terms "Decision Medicine™" - the application of highly accurate and sensitive NGS testing technology to optimize precision therapy selection for cancer patients throughout the treatment continuum, from initial tumor profiling to therapy selection and recurrence monitoring.
Illumina's financial investment represents a significant expansion of its existing partnership with Pillar, building on previous agreements established in 2017 and 2023. Ashley Van Zeeland, vice president of Corporate Development at Illumina, emphasized the strategic importance of the collaboration.
"Pillar Biosciences has become an important strategic partner to enable Illumina to provide an expanded menu of research and clinical NGS solutions, accelerating access to precision oncology," Van Zeeland stated. "Pillar's rapid NGS targeted sequencing panels alongside Illumina's state-of-the-art sequencing and bioinformatics solutions delivers rapid, cost-effective genomic profiling of tumors, which is critical to advancing personalized therapy globally."
The proceeds from this financing round will be strategically deployed to advance Pillar's commercial activities, with particular focus on expanding headcount and infrastructure to support biopharma partnerships and increase adoption of its distributable clinical testing kits.
Gang Song, Founder and Executive Chairman of Pillar Biosciences, expressed satisfaction with the company's trajectory. "We are very pleased with our commercial growth over the past few years," Song said. "We look forward to using this latest capital infusion to drive additional top-line growth as we move closer towards profitability."
Pillar's NGS testing solutions are powered by its proprietary SLIMamp® and PiVAT® technologies, which are designed to help localize the testing process, reduce diagnostic costs, and improve access and efficiency of complex NGS testing for clinicians, prescribers, and patients globally. The company currently offers more than 20 NGS testing kits available in both IVD (in vitro diagnostic) and RUO (research use only) formats, with multiple panels in various stages of development.
Benjamin Lund from Soleus Capital highlighted the market significance of Pillar's technology platform. "Access to rapid NGS testing solutions is critical to advancing precision medicine in oncology. We see Pillar's technology as a market leader, helping laboratories across the globe more effectively streamline and consolidate their molecular testing platforms, enabling faster time to results," Lund noted. "Pillar has demonstrated strong commercial growth over the past few years, including multiple biopharma collaborations."
The funding round positions Pillar to capitalize on the growing demand for precision oncology testing solutions. The company's approach to Decision Medicine™ addresses critical needs in cancer care by providing rapid, accurate genomic profiling that can inform treatment decisions and monitor disease progression.
With operations based in Natick, Massachusetts, Pillar Biosciences continues to expand its footprint in the precision medicine landscape, leveraging its proprietary technologies to improve patient outcomes through more efficient and accessible molecular testing solutions.

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