Some children with cancer are now receiving a new type of drug treatment that is far less toxic than traditional chemotherapy. This innovative treatment, known as blinatumomab or blina, has been a game-changer for patients like 11-year-old Arthur, who was treated at London's Great Ormond Street Hospital for his blood cancer. Unlike chemotherapy, which can leave patients feeling very weak and sick, blina works by targeting cancer cells directly, allowing the body's immune system to recognize and destroy them without harming healthy cells.
Arthur's experience with blina was notably different from his previous chemotherapy treatments. The drug was administered through a thin plastic tube into a vein in his arm, with the entire kit, including a battery-operated pump, carried in a backpack. This portability meant Arthur could continue his daily activities, such as playing in the park, while undergoing treatment. The therapy not only proved effective in treating his cancer but also significantly improved his quality of life, allowing him to spend more time at home with his family.
Blina is already licensed for treating adults with cancer, and experts are hopeful about its potential to safely help children as well. Around 20 centers in the UK are currently using blina off-label for children with B-ALL. The treatment represents a significant advancement in cancer therapy, offering a gentler, kinder alternative to chemotherapy, which can be harsh and debilitating for young patients.
Arthur's mother, Sandrine, shared how moving on to blina was a relief for the family, describing the chemotherapy as a 'constant challenge' that made Arthur feel worse. The success of blina in treating Arthur's cancer without the severe side effects associated with chemotherapy has brought hope to many families facing similar battles. As research continues, blina could potentially replace large portions of chemotherapy treatment, offering a brighter future for children diagnosed with cancer.
