Ultrasound Renal Denervation: A New Hope for Resistant Hypertension
A groundbreaking clinical study reveals that ultrasound renal denervation significantly reduces blood pressure in patients with resistant hypertension. This minimally invasive procedure targets overactive kidney nerves, offering a promising alternative for those who struggle with traditional treatments. The study, led by Michel Azizi and published in JAMA, highlights the procedure's effectiveness and accessibility, marking a significant advancement in hypertension management.
High blood pressure, or hypertension, is a prevalent condition that significantly increases the risk of heart disease, kidney problems, and stroke. Despite the availability of lifestyle modifications and medications, a subset of patients continues to battle uncontrolled hypertension. A recent clinical study introduces ultrasound renal denervation as a promising solution for these individuals.
Renal denervation is a minimally invasive procedure designed to target the overactive nerves in the kidneys, which play a crucial role in blood pressure regulation. The process involves inserting a small, flexible catheter through a tiny puncture in the wrist or groin, guiding it to the kidney's artery. Once positioned, the catheter delivers ultrasound or radiofrequency energy to the surrounding tissue, disrupting the nerve signals and thereby reducing blood pressure.
A study involving 224 participants with uncontrolled hypertension demonstrated the procedure's effectiveness. Results showed significant reductions in both systolic and diastolic blood pressure, either as a standalone treatment or in conjunction with medication. This study builds on previous findings, reinforcing the procedure's potential for patients with mild to moderate and resistant hypertension.
The procedure boasts several benefits, including its minimally invasive nature, precision in targeting overactive nerves, and the ability to perform it on an outpatient basis. However, it's not suitable for everyone, and patients are advised to consult their healthcare provider to assess its appropriateness for their specific condition.
While the study marks a significant step forward, further research is necessary to understand the long-term effects and safety of renal denervation fully. As the medical community continues to explore this innovative treatment, it holds the promise of becoming a vital tool in combating hypertension, especially for those who have not benefited from traditional therapies.
This study, led by Michel Azizi and published in JAMA, underscores the importance of advancing treatment options for hypertension, a condition affecting millions worldwide. As research progresses, ultrasound renal denervation could offer a new lease on life for patients struggling with resistant high blood pressure.

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Scientists find new way to treat resistant high blood pressure
knowridge.com · Jan 13, 2025
Ultrasound renal denervation, a minimally invasive procedure targeting overactive kidney nerves, significantly reduces b...