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Nature Study Validates Non-Invasive Fat Reduction Technology for Abdominal Obesity Treatment

18 days ago3 min read
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Key Insights

  • A peer-reviewed study published in Nature Scientific Reports demonstrates statistically significant abdominal fat reduction using Alma's Accent Prime ultrasound and radiofrequency technology in Korean women with abdominal obesity.

  • The clinical trial conducted at Ewha Womans University Seoul Hospital showed measurable fat layer thickness reduction through ultrasound imaging and waist circumference assessments, with high patient satisfaction and no adverse events.

  • The research addresses the growing global obesity crisis, with over 1 billion people worldwide living with obesity according to the World Health Organization, highlighting the need for safe, non-surgical treatment alternatives.

A newly published peer-reviewed study in Nature Scientific Reports provides compelling clinical evidence for the effectiveness of non-invasive energy-based technology in treating abdominal obesity. The research, conducted at Ewha Womans University Seoul Hospital, demonstrated statistically significant decreases in abdominal fat layer thickness in Korean women following treatment with Alma's Accent Prime platform.

Clinical Trial Results

Dr. Yeo Ju Sohn and Dr. Hyejin Chun from the Department of Family Medicine at Ewha Womans University College of Medicine led the research, which confirmed measurable fat layer reduction through ultrasound imaging and waist circumference assessments. The study participants, Korean women with abdominal obesity, underwent a series of ultrasound and radiofrequency treatments using the Accent Prime technology.
Patients reported high satisfaction levels and consistently strong tolerance throughout the treatment protocol. Notably, no adverse events were observed during the study period, highlighting the safety profile of the non-invasive approach.

Addressing Global Health Crisis

The publication comes at a critical time when abdominal obesity is increasingly recognized as a key contributor to cardiovascular disease and metabolic syndrome, both in South Korea and globally. According to the World Health Organization, more than 1 billion people worldwide are living with obesity—a major risk factor for type 2 diabetes, cardiovascular disease, and premature mortality.
As obesity rates continue to rise, the urgency for safe, effective, and accessible treatment options beyond surgical intervention has intensified. The study's findings offer evidence for non-invasive alternatives that could address this growing health challenge.

Technology Platform

Accent Prime combines proprietary ultrasound and radiofrequency technologies to deliver personalized, non-invasive treatments for body contouring, skin tightening, and facial rejuvenation. The platform is CE marked and approved for treatment of various indications, including facial and body contouring, skin tightening, cellulite reduction, and skin rejuvenation.
The technology has been widely adopted by leading clinics worldwide, offering flexible, combination-based protocols that support tailored treatment strategies across diverse skin types and body areas without requiring surgery or downtime. These proprietary ultrasound and radiofrequency technologies have also been clinically validated in other products from Alma's Body Contouring series, such as Alma PrimeX.

Industry Impact

"This study highlights the evolving role of non-invasive modalities in body shaping and reinforces their potential significance in the broader context of health and wellness," said Lior Dayan, CEO of Alma. "This new publication strengthens the scientific foundation supporting Alma's technologies and showcases our commitment to advancing innovation that prioritizes patient safety, enhances the treatment experience, and keeps pace with the evolving needs of modern patients."
The Nature Scientific Reports publication represents a significant milestone for evidence-based non-invasive obesity treatment approaches, potentially influencing clinical practice guidelines and treatment protocols for abdominal obesity management.
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