Association between intensive blood pressure lowering and stroke-free survival among ...

SPRINT and ACCORD-BP trials pooled for post-hoc analysis; SPRINT tested intensive BP control (SBP < 120 mmHg) vs. standard (SBP < 140 mmHg) in high CVD risk non-DM participants, while ACCORD-BP used a 2x2 factorial design in high CVD risk DM participants. Outcome of interest was stroke-free survival (SFS), analyzed using Kaplan-Meier curves and Cox proportional hazards models. Data available at https://biolincc.nhlbi.nih.gov.