In a significant move to address the global obesity crisis, Abu Dhabi-based IROS, a subsidiary of M42, has partnered with U.S.-based Halia Therapeutics to launch a groundbreaking clinical trial for obesity treatment in the UAE. The initiative comes at a crucial time, as worldwide obesity rates continue to surge, with the World Health Organization reporting 2.5 billion overweight adults globally, including 890 million living with obesity.
The UAE faces particularly challenging statistics, with approximately one-third of its adult population classified as obese. The region also grapples with an alarming type 2 diabetes prevalence of nearly 20% in some areas—more than double the global average.
Trial Design and Objectives
The clinical study will enroll 60 participants who have type 2 diabetes and meet the criteria for being either overweight or obese. Structured as a six-month investigation, the trial comprises two distinct phases. The initial phase will focus on safety parameters and pharmacokinetics, followed by a randomized placebo-controlled phase to evaluate treatment efficacy.
Key objectives include:
- Demonstrating weight loss efficacy with minimal adverse effects
- Evaluating the treatment's long-term safety profile
- Assessing impact on patients' quality of life
Strategic Significance
Islam ElTantawy, General Manager of IROS, emphasized the strategic importance of this collaboration: "Our partnership with Halia addresses a critical public health issue with the potential to improve the lives of millions struggling with obesity. This collaboration is a testament to IROS's capabilities in conducting studies of international standards."
Dr. David Bearss, CEO of Halia Therapeutics, highlighted the regional significance: "The Middle East faces unique challenges in combating obesity. Through this study, we aim to contribute to global efforts by developing new and effective treatments. Our collaboration with IROS positions us to make significant strides in understanding and treating chronic diseases at their source."
Regional Impact and Future Implications
This initiative marks a significant step in establishing the UAE as a hub for clinical research excellence. The collaboration leverages IROS's regional expertise and Halia Therapeutics' innovative approach to drug development, potentially transforming obesity treatment both locally and globally.
The study's outcomes could have far-reaching implications for healthcare systems worldwide, particularly in regions with high obesity prevalence. As the trial progresses, researchers will closely monitor results, with regular updates planned to keep the medical community informed of developments.
